How Immunotherapy Gave Jeffrey His Life Back After Melanoma Diagnosis

August 20, 2026

Melanoma Diagnosis Patient Jeff at the Memorial Cancer Institute

Story Highlights

  • Jeff was initially diagnosed with melanoma that eventually spread to his lungs and liver.
  • After 10 years of immunotherapy treatment at Memorial Cancer Institute, he is cancer free.

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If you grew up in South Florida, the sun is just part of life. For Jeff, it was everything.

The 77-year-old has spent decades outdoors. First working on a farm as a kid, then building a tree nursery he still runs today. Years of ultraviolet rays from the hot Florida sun left their mark on his fair skin. He remembers getting teased by girls when he was younger about his sun-kissed skin.

My nose would peel so often from being sunburned, I swear all the girls thought I was at the beach.

Jeff

But what seemed like a harmless rite of South Florida life would eventually lead to a life-changing diagnosis.

Jeff had a history of skin cancer, so regular skin checks were part of his routine. Ten years ago, his dermatologist found something during one of those visits, a spot Jeff hadn't noticed on his own.

The diagnosis: melanoma. Unlike other forms of skin cancer, melanoma is known for how fast it moves.

What is different about melanoma is that this cancer is much more aggressive and tends to spread to other areas of the body rather quickly.

Atif Hussein, MD | Hematologist & Oncologist | Memorial Cancer Institute

That's exactly what happened. Follow-up scans showed the cancer hadn't stayed put. It had spread to Jeff's lungs and liver.

"I ended up getting that phone call I didn't want to get," Jeff recalled. "My PET scan came back positive, and it had spread."

Fifteen years ago, a stage 4 melanoma diagnosis like Jeff's would have come with a very different outlook. Chemotherapy often failed to stop the cancer from spreading, and survival rates were grim.

But medicine had changed, and Jeff's timing was fortunate. Atif Hussein, MD, hematologist and and oncologist at Memorial Cancer Institute, recommended immunotherapy, a newer class of treatment that works differently from traditional cancer drugs. Instead of directly attacking cancer cells, immunotherapy activates the patient's own immune system to do the fighting. For the last 10 years, Jeff has been receiving regular infusions, and the results have been remarkable.

Today, his cancer is gone.

For Dr. Hussein, Jeff's journey represents something bigger than one patient's outcome. It's proof of how far cancer care has come.

"It's a privilege and honor to see someone like Jeff," he said. "A few years ago, you wouldn't have expected him to live a couple of years. Now he’s not just living; he is thriving."

Today, 60% of patients with stage 4 melanoma who receive immunotherapy live 10 years or longer. That number would have been unthinkable a decade ago.

Like any treatment, immunotherapy isn't without side effects. Because the therapy supercharges the immune system, it can sometimes cause it to mistakenly attack healthy tissue — including joints — leading to inflammation and arthritis. The good news is that in about half of patients, the arthritis goes away on its own once treatment ends.

Jeff is living proof that early detection and advances in treatment can make a difference, even when the odds seem stacked against you.

If you spend time in the Florida sun, don't skip your annual skin check. And if you've already received a diagnosis that feels overwhelming, know that options exist that didn't exist a decade ago.

 

Connect with our patient access center. We can help you find the care you need.

954-265-4325