After Melanoma Spread to Mary’s Brain, Immunotherapy Saved Her Life

August 16, 2026

Melanoma Patient Mary

Story Highlights

  • Mary was diagnosed with melanoma, the most aggressive form of skin cancer, that later spread to her brain.
  • She participated in an early clinical trial for immunotherapy at Memorial Cancer Institute and today shows no signs of cancer.

 

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Mary has spent more than 20 years doing what she loves: teaching second graders in South Florida classrooms. She knows how to hold a room, how to encourage a struggling student, and how to keep going even on the hardest days. It turns out those same skills helped save her life.

Mary was first diagnosed with melanoma, the most aggressive form of skin cancer. She navigated that diagnosis and kept moving forward. But five years later, something felt wrong.

It wasn't until five years later that I woke up with a headache, and my vision was not right.

Mary, patient
Mary at the Memorial Cancer Institute

Tests revealed the cancer had spread to her brain. For many patients, that kind of news is devastating. For Mary, it became a turning point, not a stopping point.

Mary was referred to Atif Hussein, MD, hematologist and oncologist at Memorial Cancer Institute, where she became one of the early participants in a clinical trial for immunotherapy. At the time, this approach to cancer treatment was still in its early stages. Immunotherapy works by activating the body's own immune system to recognize and destroy cancer cells, rather than relying solely on traditional chemotherapy, which often fell short against advanced melanoma.

Mary's participation in that trial put her at the forefront of what would become a revolution in cancer care.

But Dr. Hussein is the first to say that medicine is only part of the equation. He has seen it firsthand: two patients, same stage, same cancer diagnosis, very different outcomes.

 

I can see two patients, the same stage, the same cancer, in two rooms, and I leave one room saying, 'My God, this person isn't going to do great.' And then I go to the other room and say, 'Oh my God, this person is going to do great!' Positive attitude, support system, having someone with them, faith helps, praying helps.

Atif Hussein, MD | Hematologist & Oncologist | Memorial Cancer Institute
Mary with Doctor Atif Hussein

Mary didn't walk this road alone. Her faith, her family, and her community wrapped around her in ways she says made a tangible difference.

"I have a strong faith background," she said. "All the prayers, I know, made a difference. I had everyone in the community praying for me."

She leaned on every bit of her belief that she would get better, the people cheering her on, and the medical team fighting alongside her.

"You have to believe that you're going to get better," she said. "You can do this!"

Today, Mary shows no signs of cancer. She is a grandmother surrounded by four generations of family; the very life she fought to protect.

"I am very, very, very blessed," she said.

And she's still teaching, just a different kind of lesson these days. Not about reading or math, but about resilience, hope, and what it means to refuse to give up.

Connect with our patient access center. We can help you find the care you need.

954-265-4325