Hypophosphatemia
Definition
Hypophosphatemia is a low level of phosphorus in the blood.
Alternative Names
Low blood phosphate; Phosphate - low
Causes
The following may cause hypophosphatemia, including:
- Alcoholism
- Antacids
- Certain medicines including acetazolamide, foscarnet, imatinib, pentamidine, and sorafenib
- Fanconi syndrome
- Starvation
- Too little vitamin D
- Overactive parathyroid gland (hyperparathyroidism)
Symptoms
- Bone pain
- Confusion
- Muscle weakness
Exams and Tests
The doctor or nurse will examine you.
The following tests may be done:
- Kidney function tests
- Vitamin K blood test
Exam and testing may show:
- Anemia due to too many red blood cells being destroyed (hemolytic anemia)
- Heart muscle damage (cardiomyopathy)
Treatment
Treatment depends on the cause. Phosphate can be given by mouth or through a vein (IV).
Outlook (Prognosis)
How well you do depends on what is causing the condition.
When to Contact a Medical Professional
Call your health care provider if you have muscle weakness or confusion.
References
Yu ASL. Disorders of magnesium and phosphorous. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 121.
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, David R. Eltz, Stephanie Slon, and Nissi Wang.

